Preliminary Exploration of the Nutritional and Medicinal Value of Vernonia amygdalina (Bitter Leaf): Insights into Key Food Minerals and Their Health Benefits
Keywords:
Vernonia amygdalina (bitter leaf), Food minerals, Selected, health benefitsAbstract
This study explores the health importance of selected food minerals in Vernonia amygdalina, commonly known as bitter leaf, within the context of Sustainable Development Goal (SDG 3) which emphasizes good health and well-being. Our investigation highlights the chemical and nutritional components of bitter leaf, particularly its notable content of nitrogen (N), potassium (K), manganese (Mn), and iron (Fe), which are vital for various physiological functions. The analysis revealed nutrient concentrations of 4.51% N, 2.88% K, 307.52 ppm Mn, and 100.94 ppm Fe, while phosphorus (P) and magnesium (M) were found in lower amounts of 0.42% and 0.43% respectively. The potassium content is particularly significant for regulating fluid balance, muscular contractions, nerve signals, and blood pressure, thereby playing a protective role against conditions such as kidney stones and osteoporosis. Additionally, nitrogen is essential for protein synthesis and overall organism health. This study underscores the need for further exploration and utilization of Vernonia amygdalina in promoting nutritional health and its potential as a therapeutic agent.
References
Achuba, F. I. (2018). Role of bitter leaf (Vernonia amygdalina) extract in prevention of renal toxicity induced by crude petroleum contaminated diets in rats. International Journal of Veterinary Science and Medicine, 6(2), 172–177. https://doi.org/10.1016/J.IJVSM.2018.07.002
Adedapo AA, Sofidiya MO, Masika PJ, Afolayan AJ. (2008) Anti-inflammatory and analgesic activities of the aqueous extract of Acacia karroo stem bark in experimental animals. Basic Clin Pharmacol Toxicol, 103(5), 397-400.
Adedapo, A. A., Aremu, O. J., & Oyagbemi, A. A. (2014). Anti-oxidant, anti-inflammatory and antinociceptive properties of the acetone leaf extract of Vernonia amygdalina in some laboratory animals. Advanced Pharmaceutical Bulletin, 4 (Suppl 2), 591–598. https://doi.org/10.5681/apb.2014.087
Amakiri, O. K., Sunday, E. A., & Gift, W. P. (2024). Phytochemical Profile and Bioactive Compounds in Aqueous Leaf Extract of Vernonia amygdalina (Asteraceae): A GC-MS Analysis. Asian Journal of Research in Biochemistry, 14(6), 117–123. https://doi.org/10.9734/ajrb/2024/v14i6333
Anderson, J. W., Baird, P., Davis, R. H., Jr, Ferreri, S., Knudtson, M., Koraym, A., Waters, V., & Williams, C. L. (2009). Health benefits of dietary fiber. Nutrition Reviews, 67(4), 188–205. https://doi.org/10.1111/j.1753-4887.2009.00189.x
AOAC. (1990) Official Methods of Analysis, Washington DC Association of Official Analytical Chemists 14th Edition: 140- 147,
Atoyebi, J.O., Afolayan, G.O., Edagbo, D. Siddique, L. and Ajiboye, T.O. (2023) Food Mineral Changes in homegrown Basella alba species. Presentation (poster code 121) at the 6th Global Micronutrient Forum Conference, 16th – 20th October, 2023, at Hague, Netherlands.
Atoyebi, J.O., Afolayan, G.O., Iorkyar, T., Olosunde, A. Olubiyi, M., Alowonle, A. and Priscilla, A. (2023) Analysis of Important Food Minerals in Morinda citrifolia (Noni) at NACGRAB, Ibadan medicinal garden. Presentation (poster code 122) at the 6th Global Micronutrient Forum Conference, 16th – 20th October, 2023, at Hague, Netherlands.
Atoyebi, John Olayinka (2023) Micronutrients in African Bambara Groundnut (Vigna Subterranea L. verdc.) – A review. Presentation (poster code 120) at the 6th Global Micronutrient Forum Conference, 16th – 20th October, 2023, at Hague, Netherlands.
Atoyebi, O.J., Olajire, O.E., Tarfa, T.I. and Afolayan, A.O. (2023) Effect of ageing on important minerals and its retention level in Telfaria occidentalis (Ugu) leaves. Nigerian Journal of Horticultural Science, vol. 27 (1).
Degu, S., Meresa, A., Animaw, Z., Jegnie, M., Asfaw, A., & Tegegn, G. (2024). Vernonia amygdalina: a comprehensive review of the nutritional makeup, traditional medicinal use, and pharmacology of isolated phytochemicals and compounds. Frontiers in Natural Products, 3. https://doi.org/10.3389/FNTPR.2024.1347855
Edo, G. I., Samuel, P. O., Jikah, A. N., Onoharigho, F. O., Idu, L. I., Obasohan, P., Opiti, A. R., Electric, J., Ikpekoro, V. O., Otunuya, C. F., Ugbuwe, E., Ongulu, J., Ijide, M., Nwaose, I. D., Ajakaye, S. R., & Owigho, J. E. (2023). Biological and bioactive components of bitter leaf (Vernonia amygdalina leaf): Insight on health and nutritional benefits. A review. Food Chemistry Advances, 3, 100488. https://doi.org/10.1016/J.FOCHA.2023.100488
Farombi, E. O., & Owoeye, O. (2011). Antioxidative and chemopreventive properties of Vernonia amygdalina and Garcinia biflavonoid. International Journal of Environmental Research and Public Health, 8(6), 2533–2555. https://doi.org/10.3390/ijerph8062533
Food and Nutrition Board Institute of Medicine (2002). Dietary Reference intakes: Dietary functional and total fibre, National Academy Press (Washington DC).
Li, R. W., Myers, S. P., Leach, D. N., Lin, G. D., & Leach, G. (2003). A cross-cultural study: anti-inflammatory activity of Australian and Chinese plants. Journal of Ethnopharmacology, 85(1), 25–32. https://doi.org/10.1016/s0378-8741(02)00336-7
Obi, P. U., Babagana, M., Idris, I., Hadiza, M., Nma, E. M., & Nadhiekhan, A. (2024). Analysis of Proximate, Mineral and Phytochemical Composition of fresh and dry Vernonia amygdalina (Bitter Leaf) in Bida Metropolis, Niger State. UMYU Scientifica, 3(1), 88–94. https://doi.org/10.56919/usci.2431.010
Oboh, G. (2006). Nutritive value and haemolytic properties (in vitro) of the leaves of Vernonia amygdalina on human erythrocyte. Nutr. health 18 (2), 151–160. doi:10.1177/026010600601800207
Ofori, D. A., Anjarwalla, P., Jamnadass, R., Stevenson, P. C., and Smith, P. (2013). Pesticidal plant leaflet Vernonia amygdalina Del. Australia: Royal botanic garden, 1–2.
Ross, A. C., Caballero, B., Cousins, R. J., Tucker, K. L., & Ziegler, T. R. (2012). Modern Nutrition in Health and Disease: Eleventh edition. Wolters Kluwer Health Adis (ESP).
Sajo, A.O., Afolayan, G.O. and Atoyebi, O.J. (2023) Evaluation of Bambara Groundnut (Vigna Subterranea verdc.) accessions for yield performance in the rainforest and savanna agro-ecologies of Nigeria. Presentation at the 6th World Environmental Conservation Conference 18th – 21st Oct, 2023 at FUTA, Nigeria
Tura, A. M., Anbessa, M., Tulu, E. D., & Tilinti, B. Z. (2024). Exploring Vernonia amygdalina’s leaf extracts for phytochemical screening and its anti-bacterial activities. International Journal of Food Properties, 27(1), 960–974. https://doi.org/10.1080/10942912.2024.2377242
U.S. Department of Agriculture, Agricultural Research Service. (2010, August 1). Nutrient Database for Standard Reference, Release 22. Retrieved from (https://www.ars.usda.gov/)
Xu G. J. (1996) The Chinese Materia Media. Chinese Medicine and Technology Press (Beijing, China)
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